由省(sheng)部共(gong)建的“組(zu)分(fen)中藥國(guo)家重(zhong)點(dian)實(shi)(shi)驗室”位于天津中醫藥大學，是(shi)我國(guo)中醫藥領域第一個坐(zuo)落于高校的國(guo)家重(zhong)點(dian)實(shi)(shi)驗室。目前(qian)，實(shi)(shi)驗室已(yi)儲備6萬多(duo)份中藥組(zu)分(fen)，是(shi)世界最(zui)大的中藥組(zu)分(fen)庫(ku)。

在天津(jin)中(zhong)(zhong)(zhong)醫藥(yao)大學記者(zhe)看到，一(yi)瓶瓶粉末(mo)狀(zhuang)的中(zhong)(zhong)(zhong)藥(yao)組分被保(bao)存在恒(heng)溫(wen)恒(heng)濕柜中(zhong)(zhong)(zhong)。“中(zhong)(zhong)(zhong)藥(yao)組分，就(jiu)是從傳統中(zhong)(zhong)(zhong)藥(yao)中(zhong)(zhong)(zhong)提(ti)取(qu)出(chu)有(you)效的成(cheng)(cheng)分群，可在細(xi)胞和分子(zi)藥(yao)理水平上相對清(qing)楚地(di)揭示中(zhong)(zhong)(zhong)藥(yao)的藥(yao)效物質基礎及(ji)作用(yong)機制，并能根據不(bu)同病癥(zheng)重新配伍成(cheng)(cheng)方(fang)。”中(zhong)(zhong)(zhong)國(guo)工程院院士、天津(jin)中(zhong)(zhong)(zhong)醫藥(yao)大學名(ming)譽校長張伯禮介紹(shao)說，“在抗擊(ji)新冠(guan)疫情的臨床實踐中(zhong)(zhong)(zhong)，我們將虎杖、馬鞭草等有(you)效組分提(ti)取(qu)出(chu)來(lai)，制成(cheng)(cheng)‘宣肺敗毒方(fang)’，其治療新冠(guan)肺炎療效確切。”

5月29日(ri)，第二屆團泊湖中(zhong)(zhong)醫(yi)藥現(xian)(xian)代(dai)(dai)(dai)化論壇暨新時(shi)代(dai)(dai)(dai)中(zhong)(zhong)醫(yi)藥高質量(liang)發展(zhan)(zhan)關鍵科學(xue)(xue)問題研(yan)討會在天津召開。專家(jia)指(zhi)出(chu)，如何用現(xian)(xian)代(dai)(dai)(dai)科學(xue)(xue)解讀中(zhong)(zhong)醫(yi)藥學(xue)(xue)原理，把中(zhong)(zhong)醫(yi)藥的(de)(de)療(liao)效優勢“說(shuo)明白、講清楚”，更好服務人民健(jian)康，是(shi)新時(shi)代(dai)(dai)(dai)中(zhong)(zhong)醫(yi)藥傳承創新發展(zhan)(zhan)的(de)(de)根(gen)本(ben)要求，也是(shi)推動中(zhong)(zhong)醫(yi)藥現(xian)(xian)代(dai)(dai)(dai)化、產業化和國際化發展(zhan)(zhan)的(de)(de)必然要求。圍繞新時(shi)代(dai)(dai)(dai)中(zhong)(zhong)醫(yi)藥發展(zhan)(zhan)的(de)(de)關鍵問題，加強(qiang)基礎研(yan)究，發掘(jue)中(zhong)(zhong)醫(yi)藥的(de)(de)時(shi)代(dai)(dai)(dai)價(jia)值，促(cu)進(jin)中(zhong)(zhong)醫(yi)藥傳承創新發展(zhan)(zhan)是(shi)當前推進(jin)中(zhong)(zhong)醫(yi)藥現(xian)(xian)代(dai)(dai)(dai)化發展(zhan)(zhan)的(de)(de)題中(zhong)(zhong)之(zhi)義。

“多年來(lai)，天津立(li)足行業優勢(shi)，面(mian)向(xiang)國(guo)家需求，從不同層面(mian)開(kai)(kai)展了(le)(le)(le)(le)卓有成(cheng)(cheng)效(xiao)的(de)(de)工作，并取(qu)得了(le)(le)(le)(le)豐碩成(cheng)(cheng)果。如何培育質(zhi)優高效(xiao)的(de)(de)中(zhong)(zhong)成(cheng)(cheng)藥(yao)大品種，讓(rang)百(bai)姓用‘好藥(yao)’，一(yi)直是(shi)中(zhong)(zhong)醫藥(yao)行業發(fa)展面(mian)臨的(de)(de)重要任務。”張(zhang)伯禮在(zai)多年前就為(wei)實現中(zhong)(zhong)藥(yao)產(chan)業跨(kua)越式發(fa)展開(kai)(kai)出了(le)(le)(le)(le)“處方”。他帶(dai)領團隊完成(cheng)(cheng)了(le)(le)(le)(le)“中(zhong)(zhong)成(cheng)(cheng)藥(yao)二(er)次(ci)開(kai)(kai)發(fa)核心技(ji)術(shu)體(ti)系(xi)創研及其產(chan)業化(hua)”項目，構建了(le)(le)(le)(le)臨床準確(que)定位、藥(yao)效(xiao)物質(zhi)整體(ti)系(xi)統辨析(xi)、網絡藥(yao)理學、工藝品質(zhi)調優和數字化(hua)全(quan)程質(zhi)控等五大核心技(ji)術(shu)體(ti)系(xi)，實現了(le)(le)(le)(le)從原料到制(zhi)劑(ji)的(de)(de)全(quan)程質(zhi)量控制(zhi)，為(wei)古(gu)老的(de)(de)中(zhong)(zhong)藥(yao)賦予了(le)(le)(le)(le)現代科技(ji)內(nei)涵(han)。該(gai)項目歷時8年，技(ji)術(shu)已在(zai)全(quan)國(guo)19個省市推廣(guang)。

通過推廣實施(shi)中(zhong)(zhong)(zhong)藥(yao)二(er)次(ci)開發戰略，項(xiang)目培(pei)育了中(zhong)(zhong)(zhong)藥(yao)大品(pin)(pin)種群，行業(ye)集中(zhong)(zhong)(zhong)度(du)得到有效提(ti)升(sheng)。據統計，銷售額過億元的(de)中(zhong)(zhong)(zhong)藥(yao)品(pin)(pin)種由2006年的(de)100多(duo)個增加到350余個。“中(zhong)(zhong)(zhong)藥(yao)二(er)次(ci)開發推動中(zhong)(zhong)(zhong)藥(yao)產業(ye)技(ji)術(shu)(shu)升(sheng)級(ji)換代，產生了巨(ju)大的(de)社會經濟效益(yi)，項(xiang)目榮獲國家科(ke)學技(ji)術(shu)(shu)進步獎(jiang)一等(deng)獎(jiang)。”天津(jin)市(shi)衛生健康委(wei)中(zhong)(zhong)(zhong)醫處(chu)處(chu)長于春泉向記者介(jie)紹。

中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)是中(zhong)(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)(yao)(yao)(yao)的(de)(de)物(wu)質(zhi)(zhi)基(ji)礎，其質(zhi)(zhi)量(liang)(liang)直接影響著(zhu)中(zhong)(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)(yao)(yao)(yao)的(de)(de)高質(zhi)(zhi)量(liang)(liang)發展。長(chang)期以來，中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)質(zhi)(zhi)量(liang)(liang)魚龍(long)混雜(za)，參差(cha)不齊，阻礙了(le)行業(ye)的(de)(de)健康(kang)發展。為此，由張伯禮院士等(deng)專家牽頭成立的(de)(de)國家中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)標準化與(yu)質(zhi)(zhi)量(liang)(liang)評估創新聯(lian)盟(meng)(meng)從把(ba)控(kong)中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)源(yuan)頭出(chu)(chu)發，聯(lian)合數十家知名(ming)中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)企業(ye)，以中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)基(ji)地共(gong)建共(gong)享的(de)(de)方(fang)式，促進(jin)中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)規(gui)范化生產，把(ba)控(kong)中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)質(zhi)(zhi)量(liang)(liang)、產量(liang)(liang)。2018年聯(lian)盟(meng)(meng)首次(ci)提出(chu)(chu)了(le)優質(zhi)(zhi)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)“三無(wu)(wu)一(yi)全”的(de)(de)概念，要(yao)(yao)求(qiu)聯(lian)盟(meng)(meng)成員單位的(de)(de)中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)材(cai)(cai)要(yao)(yao)率先(xian)(xian)達(da)到“無(wu)(wu)硫(liu)黃加工，無(wu)(wu)黃曲霉(mei)素超標，無(wu)(wu)公害，全過程可追溯”的(de)(de)標準。“聯(lian)盟(meng)(meng)大(da)力提倡(chang)優質(zhi)(zhi)優價、優質(zhi)(zhi)優先(xian)(xian)。天津、上海、浙江、福建等(deng)地在聯(lian)盟(meng)(meng)的(de)(de)推動下已經開始鼓勵優先(xian)(xian)采用‘三無(wu)(wu)一(yi)全’等(deng)質(zhi)(zhi)量(liang)(liang)可溯源(yuan)的(de)(de)中(zhong)(zhong)(zhong)(zhong)藥(yao)(yao)(yao)(yao)(yao)飲片，為全行業(ye)發展起到了(le)示范作用。”天津中(zhong)(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)(yao)(yao)(yao)大(da)學科技處處長(chang)劉(liu)二偉向記者(zhe)介(jie)紹。

把中(zhong)醫(yi)(yi)藥(yao)(yao)的療(liao)效“說明白、講清楚”是推動(dong)中(zhong)醫(yi)(yi)藥(yao)(yao)現(xian)代化進程的基礎，也是中(zhong)醫(yi)(yi)藥(yao)(yao)高質(zhi)量(liang)發展的必然要求。記者在(zai)采訪中(zhong)看到，天津中(zhong)醫(yi)(yi)藥(yao)(yao)行業(ye)正全(quan)面(mian)發力，推動(dong)傳統(tong)優勢產(chan)業(ye)提檔升級(ji)，打造中(zhong)醫(yi)(yi)藥(yao)(yao)現(xian)代化高地。